1. Purpose

This document is meant for the administrators of the BioMS application. This document describes the process of deploying the BioMS application and regular administration activities to be performed on the BioMS application.

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1. One Oracle 10g/11g Schema with permissions for creating table and sequences
2. 4 Server machine with the following minimum configuration
   
   1. Dual core, 4GB RAM, 50 GB HDD x 2 – for BioMS cluster nodes
      
      1. Software required on these machines : RHEL 5.0+, Oracle Client (sqlldr, tnsping, sqlplus), ftp , p7zip, jboss 5.1
      2. Open the following ports for UDP traffic on both nodes. This is required for the bioms jboss cluster to work.
         
         1. 45688

         2. 45710

         3. 44401

         4. 44402

         5. 7900

   2. Dual core, 4GB RAM, 50 GB HDDx1 -for caTissue 2.0A on BioMS, this machine should have oracle client installed on it. This is required for installing caTissue.
      
      1. Software required on this machine : RHEL 5.0+, Oracle Client (tnsping, sqlplus)
   3. Dual Core, 1GB RAM, 50 GB HDD x 1 – for the apache load balancer
      
      1. Software required on this machine : RHEL 5.0+,apache

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Get the caTissue 2.0A installer from sftp://files.cbmi.wucon.wustl.edu:/files/bioms/1.0/final/caTISSUE_Suite_v2.0_caTISSUE_Suite_v2.0_Installable.zip and unpack it on caTissue2.0A on BioMS server. Follow the caTissue 2.0 installation instruction to install caTissue to the BioMS Oracle DB.

Change A simple setup of caTissue requires change the following properties in the install.properties, for other properties usually the default values are good.

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load.balancer.url=<url at which users will be accessing this catissue, e.g url of the loadbalancer apache server, or external url of the catissue>

To install run ant install from the installer unpack folder


To upgrade an existing installation to a newer build , update the install.properties as detailed above and run ant upgrade:jboss from the installer unpack folder. Make sure the database properties in the install.properties is pointing to the database where the current catissue is running.

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JAVA_OPTS="-Xms128m -Xmx2048m -XX:MaxPermSize=1024m -Dorg.jboss.resolver.warning=true -Dsun.rmi.dgc.client.gcInterval=3600000 -Dsun.rmi.dgc.server.gcInterval=3600000 -Dgov.nih.nci.security.configFile=$HOME/.bioms/conf/ApplicationSecurityConfig.xml"

7. Edit JBOSS_HOME<jbosshome>/server/bioms-node1/conf/login-config.xml and update the database connection details under the application-policy element with name 'bms' to point to the BioMS database schema.

8. Edit JBOSS_HOME/server/bioms-node1/deploy/bioms-ds.xml and update the database connection details

9. Copy BIOMS_INSTALL_HOME/.bioms to users home folder ($HOME)

10. Edit $HOME/.bioms/ApplicationSecurityConfig.xml and replace ${user.home} with the home directory path of the user.

11. Edit $HOME/.bioms/bioms-config.groovy and update the following properties

 a. datasource section with the database connection details for the BioMS database schema

 b. set bms.baseURL to the base URL at which the application will be accessed by users. This should be set to the base load balancer URL. If the application is configured for external access then this url should be the external URL of the application. (e.g. http://biomstest.wuslt.edu/bioms)

12. Start the JBoss Server bioms-bioms-node1

run.sh –b0.0.0.0 –cbioms-node1 -u239.255.100.100 –gBioMSPartition -Djboss.messaging.ServerPeerID=1

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7. Setup BioMS on Bioms-node2

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In node2 perform the following additional configuration.

1 Edit Edit $HOME/.bioms/bioms-config.groovy and update the following configuration

In the quartz section set autoStartup=false

Start the BioMS Node with the command

run.sh –b0.0.0.0 –cbioms-node2 -u239.255.100.100 –gBioMSPartition -Djboss.messaging.ServerPeerID=2

Make sure the -u and -g options values are matching with the values used in starting node1 and ServerPeerID is different

Once the bioms-node2 server is started make sure bioms-node2 bioms is accessible at http://<bioms-node2-server>:8080/bioms

8. Setup the Apache load balancer

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deploy/cluster/jgroups-channelfactory.sar/META-INF/jgroups-channelfactory-stacks.xml and add line

bind_port="44401"

after the lines

<UDP
singleton_name="shared-udp"
mcast_port="${jboss.jgroups.udp.mcast_port:45688}"
mcast_addr="${jboss.partition.udpGroup:228.11.11.11}"

8. Edit JBOSS_HOME/server/bioms-node1/conf/login-config.xml and update the database connection details under the application-policy element with name 'bms' to point to the BioMS database schema.

9. Edit JBOSS_HOME/server/bioms-node1/deploy/bioms-ds.xml and update the database connection details

10. Copy BIOMS_INSTALL_HOME/.bioms to users home folder ($HOME)

11. Edit $HOME/.bioms/ApplicationSecurityConfig.xml and replace ${user.home} with the home directory path of the user.

12. Edit $HOME/.bioms/bioms-config.groovy and update the following properties

 a. datasource section with the database connection details for the BioMS database schema

 b. set bms.baseURL to the base URL at which the application will be accessed by users. This should be set to the base load balancer URL. If the application is configured for external access then this url should be the external URL of the application. (e.g. http://biomstest.wuslt.edu/bioms)

12. Start the JBoss Server bioms-bioms-node1

run.sh –b0.0.0.0 –cbioms-node1 -u239.255.100.100 –gBioMSPartition -Djboss.messaging.ServerPeerID=1

This will start the server and the BioMS application deployed. Try accessing the BioMS application at url http://<bioms-node1-server>:8080/bioms. Login to the application using credentials admin@bms.com/Passw0rd and we should see a page similar to the following snapshot.

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7. Setup BioMS on Bioms-node2

Follow the same steps give in Section 3.3 substituting all bioms-node1 with bioms-node2 to setup second node of the BioMS cluster on server BioMS node2

In node2 perform the following additional configuration.

1. Edit Edit $HOME/.bioms/bioms-config.groovy and update the following configuration

In the quartz section set autoStartup=false

Start the BioMS Node with the command

run.sh –b0.0.0.0 –cbioms-node2 -u239.255.100.100 –gBioMSPartition -Djboss.messaging.ServerPeerID=2

Make sure the -u and -g options values are matching with the values used in starting node1 and ServerPeerID is different

Once the bioms-node2 server is started make sure bioms-node2 bioms is accessible at http://<bioms-node2-server>:8080/bioms

8. Setup the Apache load balancer

Install apache HTTP server and configure mod_jk module and use the following mod_jk worker configuration

 # Define list of workers that will be used
 # for mapping requests
 worker.list=loadbalancer,status
 
 # Define Bioms-node1
 # modify the host as your host IP or DNS name.
 worker.bioms-node1.port=8009
 worker.bioms-node2node1.host=<bioms-node2node1-host> 
 worker.bioms-node2node1.type=ajp13
 worker.bioms-node2node1.lbfactor=1
 worker.bioms-node2node1.cachesize=10
 
 # Define LoadBioms-balancingnode2
 behaviour
 worker.loadbalancer.type=lb# modify the host as your host IP or DNS name.
 worker.bioms-node2.port=8009
 worker.loadbalancer.balance_workers=bioms-node1,bioms-node2.host=<bioms-node2-host> 
 worker.bioms-node2.type=ajp13
 worker.loadbalancer.sticky_sessionbioms-node2.lbfactor=1
 
 # worker.bioms-node2.cachesize=10
 
 # Load-balancing behaviour
 worker.loadbalancer.type=lb
 worker.loadbalancer.balance_workers=bioms-node1,bioms-node2
 worker.loadbalancer.sticky_session=1
 
 # Status worker for managing load balancer
 worker.status.type=status

Configure the worker uri map in Apache load balancer.Add the following uriworkermap.properties file in apache config

/bioms=loadbalancer

/bioms/*=loadbalancer

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To configure nightly mayo auth data sync cron job run 'crontab -e' command and and the following to the end of the file and save

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0 22 * * * $HOME/.bioms/mayo-auth-sync/sync-mayo-auth-data.sh > $HOME/.bioms/mayo-auth-sync/log/mayo-auth-sync.log.`date +\%y\%m\%d-\%H\%M\%S` 2>&1

This will run the Mayo auth data sync every night at 10PM and output of the run would be logged to a file of the $HOME/.bioms/mayo-auth-sync/log/mayo-auth-sync.log.YYMMDD-HHmmSS

To test the sync job and trigger an immediate sync of the auth data run

$HOME/.bioms/mayo-auth-sync/sync-mayo-auth-data.sh > $HOME/.bioms/mayo-auth-sync/log/mayo-auth-sync.log.`date +\%y\%m\%d-\%H\%M\%S` 2>&1

Once the execution is complete check the log file at $HOME/.bioms/mayo-auth-sync/log/mayo-auth-sync.log.nnnnnnnn and make sure there are no errors in the log.

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1. Set the following environment variable in $HOEM/.bash_profilebashrc

      export CTSU_HOME=$HOME/.bioms/conf/CTEP

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Here is the SQL for the inserting the repository data into the DB

Insert into BMS_REMOTE_REPOSITORY (ID,NAME,JMS_QUEUE_NAME,AUTHKEY,STATUS,LAST_HEART_BEAT_TIME,CONTACT) values ((select max(id)+1 from BMS_REMOTE_REPOSITORY),'<repo-name>','<repo-name>','<authkey>',1,SYSDATE,'<contact_emails>');

Securely share the <repo-name> and <authkey> and the bioms application url (the loadbalancer url) with the repository caTissue admin. They would need to update the bioms-adaptor.properties with these details.
Once the bioms-adaptor is setup properly at the repository caTissue and started you should see message like

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1. Request the caTissue Admin to create Repository Site along with the coordinator user in the catissue and note the identifier of the Repository Site.
2. Get the details of the Repository Site and the Coordinator user Name from the repository caTissue admin.
3. Create a Site of type Repository in BioMS via the 'caTissue2.0A on BioMS' caTissue instance and select the coordinator user created by the caTissue admin as the coordinator (this user would have been synced to BioMS automatically). Note the id of the site as <bms_repo_site_id> just created from caTissue2.0A on BioMS.

4. Link the repository site created above with the caTissue remote repository created in Step 13.1. For this insert a new row into the BMS_REMOTE_REPOSITORY_SITE table as shown below.

   REMOTE_REPOSITORY_ID	SITE_ID
   <id of the remote repo entry for the remote repo>	<bms_repo_site_id>

   Here is the SQL command for this insert:

   Code Block
   Insert into BMS_REMOTE_REPOSITORY_SITE (REMOTE_REPOSITORY_ID,SITE_ID) values ((select id

   from BMS

   from BMS_REMOTE_REPOSITORY where name=<repo-name>),<bms_repo_site_id>);

    

5. (To be performed on the caTissue repository) Map the new Site created in BioMS with the Repository with the same name corresponding repository Site created in caTissue per step 1. For this request the repository caTissue admin to insert the following row data into BMS_CATISSUE_ENTITY table in the repository caTissue data base

   ID	ENTITY_TYPE	BMS_ID	CATISSUE_ID
   BMS_CATISSUE_ENTITY_MAP_SEQ.nextval	edu.wustl.catissuecore.domain.Site	<bms_repo_site_id>	<id_of_repo_site_in_catissue>

   Here is the SQL insert command for the same.

   Code Block
   Insert into BMS_CATISSUE_ENTITY_MAP (ID,ENTITY_TYPE,BMS_ID,CATISSUE_ID) values (BMS_CATISSUE_ENTITY_MAP_SEQ.NEXTVAL,'edu.wustl.catissuecore.domain.Site',<bms_repo_site_id>,<catissue_repo_site_id>);

   We should now be able to create studies with the new repository as the ship to site for specimen and sync the studies. When the study is synced study should show up in the caTissue.

   13.3. Building and rolling out new Study

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Participant registrations usually comes from Mayo Rando Node applications. But until the Mayo Rando Node integration is enables, BioMS admin can register participants to study via the participant registration page provided in BioMS. The participant registration page can be accessed from the ADMIN TASKS menu group when logged in as BioMS Admin.

13.4. Watching for Sync issues

BioMS admin can see if there are any happening during syncing of data between BioMS and repository caTissue from the Sync Errors menu in the ADMIN TASKS menu group accessible only for BioMS admins. This page lists all the errors occurred during the sync with the sync message and the error details including any stack trace. BioMS admin should review this list of error at least once in a day to make sure sync functions are working properly.Admin.

13.4. Watching for Sync issues

BioMS admin can see if there are any happening during syncing of data between BioMS and repository caTissue from the Sync Errors menu in the ADMIN TASKS menu group accessible only for BioMS admins. This page lists all the errors occurred during the sync with the sync message and the error details including any stack trace.

BioMS admin should review this list of error at least once in a day to make sure sync functions are working properly.

 13.5. CALGB Incremental Registration load

The CALGB incremental registration load is configured in alliance bioMs (dev) server.

The load script /usr/local/bms/.bioms/calgb-reg-sync/load-incr-calgb-regdumps.sh  is configured to run at 15 minutes on the hours 7AM- 8PM EST Monday-Friday.
 
The script downloads the incremental registrations dump files from  ftp.mayo.edu and attempts to load them into bioms QA deployment.

The logs from each execution of the incremental load goes into the folder alliancebms@/usr/local/bms/.bioms/calgb-reg-sync/log